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This might potentially lead to reduced infiltration of inflammatory cells in the lungs of mice with lung damage and lower levels of TNF-1 and IL-6 production to minimize damage

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SNAP-GLP1R:CHO-K1 cells were incubated with LUXendin492 (LUX492), LUXendin551 (LUX551), and LUXendin615 (LUX615) before orthogonal SNAP-labeling with either cell-impermeable SBG-TMR or SBG-SiR and confocal imaging (nuclei were stained using Hoechst33342) (scale bar = 10 m) (n = three images from experiments performed in duplicate)

Activation of TLRs is a cornerstone of innate immunity, triggering key defense responses against invading pathogens (260)