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In rodent and primate metabolic models, amylin analogue administration has been shown to attenuate glucagon-driven hepatic glucose output and reduce postprandial glycemic excursions, independently of insulin secretion (Verchere et al., Proceedings of the National Academy of Sciences, 1996

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Topical formulations (serums, foams, microemulsions): GHK-Cu is already used cosmetically for skin rejuvenation