Full therapeutic effects for weight management should be evaluated after 12 weeks at a maintenance dose (typically 10-15 mg weekly), while glycemic response for diabetes is assessed after 3-6 months on a stable dose
Nitheesh Y, Pradhan R, Hejmady S, Taliyan R, Singhvi G, Alexander A, et al
and muscle strength, function, and quality of life did not improve, so the fat-free mass gains should be interpreted with caution, he says
Pregnancy and Breastfeeding Neither Semaglutide nor Tirzepatide is recommended for those who are currently pregnant, planning to become pregnant within the next six months, or breastfeeding , due to limited research on safety in these conditions
PAPs are harder to qualify for (strict income limits and medical criteria), but if you do qualify, you might receive the medication free or at a very low cost