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Gastroenterology 127 , 16851694 (2004)
Another piece of research from the same trial suggested weight loss using semaglutide could be sustained for up to four years in adults who are overweight, or obese
By promoting fat burning, it helps increase calorie use and supports the reduction of body fat
The NEJM authors reported the most common side effects as mild-to-moderate gastrointestinal events, with the trial discontinued due to adverse events in 4.4% to 7.8% of participants receiving orforglipron compared to 1.4% given the placebo
Some may experience mini plateaus (short-term stalls) before resuming weight loss, while others reach a more permanent plateau
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