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This is not only a regulatory and consumer preference consideration

The SURMOUNT trial showed 20% net weight loss with tirzepatide in patients with overweight/obesity, nearly as effective as metabolic surgery

Moreover, HIF-1 plays a central role in regulating immune evasion, glycolysis, metastasis, and tumor progression, particularly in triple-negative breast cancer (TNBC), highlighting its broad impact on tumor biology [162]

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DOI.org (Crossref) , For your further reading: For your further reading: For your further reading: 9 Sheikh, N., et al