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Continue eating if youre constipated, but avoid foods that can worsen constipation (for example, processed foods, low-fiber foods)

Both peptides increase GH levels, but Ipamorelin is considered more selective and does not significantly affect other hormones such as cortisol and prolactin

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13 When comparing the active GLP-2R structure with the GLP-1-bound GLP-1R structure, 13 the extracellular end of TM1 in GLP-2R is extended by six additional residues, thereby bending toward GLP-2 with the formation of additional hydrogen bond and hydrophobic contacts

The economics differ significantly because tirzepatide is available as a commercial pharmaceutical product while retatrutide is currently a research compound