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and later in 2025 it received FDA approval for obesity
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It has been also shown to upregulate mitochondrial transcription factor A (TFAM) (Sreekumar et al., 2016), known to play a crucial role in stabilizing mtDNA through the formation of nucleoids, which are important to counteract mtDNA release (Li F et al., 2020), which serve as markers of oxidative stress (e.g., Lei and Rao, 2022)
International Journal of Chemical Engineering and Applications , 7 , 2226
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