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Administration methods include intramuscular (IM) and intravenous (IV) injections
Reduced NNMT in adipose tissue was associated with increased expression of polyamine flux genes and increased adipocyte energy expenditure connecting NNMT inhibition to "futile cycling" mechanisms that consume energy without productive metabolic output
Less common symptoms include headaches, a thumping heart (palpitations), altered taste, loss of appetite, pale appearance, sore mouth or tongue and ringing in the ears (tinnitus)
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