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GLP-1 exerts several key physiologic effects: Increases glucose-dependent insulin secretion Suppresses inappropriate glucagon release Delays gastric emptying Promotes satiety and reduces appetite Pharmacologic GLP-1 receptor agonists, including semaglutide, liraglutide, and tirzepatide, are engineered to resist DPP-4 degradation, allowing them to persist for hours to days

Accordingly, GLP-1RAs have been increasingly used in the treatment of PCOS because of their ability to reduce weight and improve IR (155159)

The following procedure represents a proven laboratory standard

Another study found that liraglutide improves cognitive decline in patients with Type 2 diabetes mellitus

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