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The same review notes that the Philippine Food and Drug Administration warns against IV glutathione for skin lightening due to risks of liver damage and the absence of clinical proof

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Interestingly, 6 of the 8 studies included in this systematic review reporting baseline CRP values showed elevated levels (between 3 and 4.8 mg/L), reflecting that the populations evaluated, mostly patients with T2DM and obesity, possess a chronic inflammatory state

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