The kidneys benefit through mechanisms that are largely body-weight-independent, while some cardiovascular benefit in leaner patients may be attenuated
Javaheri S, Barbe F, Campos-Rodriguez F, Dempsey JA, Khayat R, Javaheri S, et al
Hajjar et al., 2018), reduced verbal fluency(Pia et al., 2016), reduced motor control(Hockenberry et al., 2015
Randomised placebo-controlled multicentre trial to evaluate the efficacy and safety of JTR-161, allogeneic human dental pulp stem cells, in patients with acute ischaemic stroke (J-REPAIR)
Additional studies are needed to evaluate safety, efficacy, and proper use of GLP-1 agonists for dermatologic conditions to consider expanding their approval beyond T2DM and weight loss