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Thiamine deficiency adversely affects the activity levels of these enzymes, with TK, through thiamine-dependent erythrocyte transketolase (ETK) activity, common biomarkers of thiamine status, since it is particularly sensitive to thiamine levels and AKD often exhibiting the earliest detectable changes (41)
10.3390/biomedicines11092444 42
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Also, the stronger absorption can increase the possibility of side effects (though DSIPs side-effect profile remains modestly characterized)
Wen B, Zhao L, Zhao H, Wang X
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