Looking away from the injection site as the needle goes in can reduce anxiety significantly
Chen J, Xie JJ, Shi KS, Gu YT, Wu CC, Xuan J, Ren Y, Chen L, Wu YS, Zhang XL, Xiao J, Wang DZ, Wang XY (2018) Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat
GLP-1Rs are expressed in the pancreas, intestinal intraepithelial lymphocytes, myocardium, adipose tissue, kidney, liver, blood vessels, lungs and in the CNS.2,3 Although GLP-1 is known for its incretin effect, which it shares with glucose-dependent insulinotropic peptide (GIP), the intake-regulating action, essential for its efficacy against obesity, occurs through its interaction with receptors located in the CNS.1,5 The GLP-1 peptide can reach the central nervous system (CNS) via peripheral vagal afferents, which transmit its action through the nodose ganglion to the nucleus tactus solitarius (NTS)
CCL11 is a potent inflammatory chemokine heavily linked to age-related neurodegeneration and the breakdown of the blood-brain barrier
Manije Darooghegi Mofrad, Hadis Mozaffari, Seyed Mohammad Mousavi, Ali Sheikhi & Alireza Milajerdi (2020) The effects of psyllium supplementation on body weight, body mass index and waist circumference in adults: A systematic review and dose-response meta-analysis of randomized controlled trials, Critical Reviews in Food Science and Nutrition, 60:5, 859-872 Chromium: Fact Sheet for Consumers. NIH Office of Dietary Supplements
