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You can do this a number of ways

Your doctor will monitor your thyroid function and make adjustments as needed

The adaptation process happens through a mechanism called tachyphylaxis, where your GLP-1 and GIP receptors become less sensitive to constant stimulation, reducing the severity of side effects while maintaining weight-loss efficacy

Also, certain foods are more likely to trigger heartburn including tomato sauces and spicy foods consider avoiding these while your digestive system gets used to your medication