Some of the major market players in the GLP-1 receptor agonist industry include Amgen Inc., Eli Lilly and Company, Hanmi Pharm Co., Ltd., Jiangsu Hengrui Pharmaceuticals Co., Ltd., Novo Nordisk A/S, Paige Biomedicine (Suzhou) Co., Ltd., and Sanofi S.A
It belongs to a class of medications known as GLP-1 receptor agonists, which also includes Ozempic, Mounjaro, Zepbound, Trulicity, Rybelsus, Saxenda and Victoza
Patel H, Chen J, Das KC, Kavdia M (2013) Hyperglycemia induces differential change in oxidative stress at gene expression and functional levels in HUVEC and HMVEC
Reason for escalation: gradual titration helps reduce GI-related effects and aligns with clinical study structures
Current knowledge, future clinical and translational research questions