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Semaglutide GLP-1 is administered as a once-weekly injection and has been clinically proven to support significant weight reduction when paired with personalized dietary and lifestyle modifications

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To maximise the cardiovascular benefits of GLP-1 RAs at a population level, strategies can be used to improve tolerability, such as patient counselling, gradual dose escalation and the use of long-acting formulations [27]

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The realistic ways it could affect weight (indirectly) When evaluating weight-loss claims, it's helpful to think in terms of systems rather than slogans