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8.5 Geriatric Use Population pharmacokinetic analysis of patients ranging from 22 to 73 years of age suggests that age does not influence the pharmacokinetic properties of exenatide [see Clinical Pharmacology (12.3)]
The hormone slows gastric emptying, prolonging the feeling of fullness after meals, and acts on appetite centres in the brain to reduce food intake
Inhibition of histone deacetylase activity down-regulates urokinase plasminogen activator and matrix metalloproteinase-9 expression in gastric cancer
Small, frequent meals also help
Key takeaways Health insurance companies may stop covering GLP-1 medications for weight loss due to their rising costs and questions about their necessity
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