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Evidence that the major degradation product of glucose-dependent insulinotropic polypeptide, GIP(3-42), is a GIP receptor antagonist in vivo

Reconstitute the 1mg lyophilized vial in 10mM hydrochloric acid (HCl) at a concentration of 0.5-1.0 mg/mL to ensure complete solubilization, as IGF-1 LR3's isoelectric point near pH 8.4 makes it poorly soluble in neutral buffers and prone to aggregation at physiological pH

If gastrointestinal symptoms persist beyond the first week or two, cutting the dose in half is usually more effective than pushing through, and reintroducing it at a slower pace tends to work better than stopping entirely

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