Inflammation as a central mechanism in Alzheimers disease
Semaglutide Building upon the pharmacological success of liraglutide, Novo Nordisk developed semaglutide with strategic structural modifications to enhance its pharmacokinetic profile
Vegetarians and Vegans Vitamin B12 isnt produced by our bodies despite being one of the most important nutrients needed for everyday function
Retatrutide is a peptide that mimics three hormones in the body: GLP-1, GIP, and glucagon Your gut releases GLP-1 after you eat, and it helps you feel full, slows how quickly food leaves your stomach, tells your pancreas to release insulin when blood sugar is high, and reduces how much sugar your liver releases into your blood
sgRNA constructs and gene expressing codon optimized (OPT) plasmid constructs sgRNA control and constructs against CBS and L2HGDH were designed targeting GTATTACTGATATTGGTGGG (sgControl) (#230080, Addgene), GGAGCAGACAACCTACGAGG (sg CBS -1) (#230081, Addgene), TGGCAGTGCTGGCAGCACGG (sg CBS -2) (#230082, Addgene), GATATAGTCATCGTTGGTGG (sg L2HGDH -1) (#230083, Addgene), and CACCAGACTGGACATAACAG (sg L2HGDH -2) (#230084, Addgene) and constructed in lentiCRISPR v2-Blast (#83480, Addgene) for Blasticidin selection at a final concentration of 5 g/ml