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538 Activation of CaMK signaling leads to the release of HDAC-5, which in turn activates GLUT4 in skeletal muscle to stimulate glucose uptake

doi: 10.1016/j.diabres.2019.05.001 51 PerkovicV.De ZeeuwD.MahaffeyK

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This insulin deficiency may cause substantial lipolysis in adipose tissue, releasing large amounts of fatty acids that, if not efficiently utilized, could impair cellular functions

Collagen is one of two proteins in the skin that keep it plump and give it structure