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This binding transcriptionally upregulates the expression of a series of key genes, including GCLC, GCLM (the light chain of GCLC), and xCT (system xc, responsible for cysteine uptake), thereby increasing GSH synthesis and cysteine uptake, thereby strengthening the cell's antioxidant defenses

Farveh Yahyapoor, Alireza Sedaghat, Awat Feizi et Mohammad Bagherniya, The effects of l-Carnitine supplementation on inflammatory markers, clinical status, and 28 days mortality in critically ill patients: A double-blind, randomized, placebo-controlled trial , Clinical nutrition ESPEN , vol

, 70 , 3431-3434, doi: Mancilla, H., Maldonado, R., Cereceda, K., Villarroel-Espindola, F., De Oca, M

doi: 10.3390/diagnostics12051095 20 ChangC-JHungL-YKogelnikAMKaufmanDAiyarRSChuAMet al