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In one study of perceptions of long-acting injections (LAIs) compared to pills, for example, the perceived advantage for LAI over pills and the belief about the better efficiency of LAI were the main factors that drove the preference for LAI

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Further mechanistic studies showed that NNMTi increases intracellular NAD levels and activates the SIRT1 pathway by inhibiting NNMT, thereby suppressing the transcription of adipogenic genes and preventing the maturation of preadipocytes.This research provides a new perspective for understanding the molecular mechanism of adipocyte differentiation, confirms the key role of NNMTi in regulating adipogenesis, and lays a foundation for subsequent obesity intervention studies