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5.2.2 Impact of comorbidities commonly seen in patients with T2D on oral semaglutide absorption Upper GI disease and hepatic and renal impairment are common comorbidities in patients with T2D that may influence the pharmacokinetics of antidiabetes drugs [68, 69]
Prevalence increased from 9.4% to 11.6% when esophagogastroduodenoscopy evaluated upper GI symptoms
Severe bloating, persistent vomiting, or failure to pass stool or gas , which may indicate bowel obstruction or severe gastroparesis
But in some cases, it can be a sign of something more serious, like ocular rosacea , a condition characterized by significant inflammation of the eye and its surrounding area
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