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SAM is synthesized from methionine via an energy-consuming reaction
J Biol Chem 1996
A review published in the journal Diabetes Care found an increased risk of pancreatitis in patients using GLP-1 receptor agonists like Ozempic, although the absolute risk remains low
Its given weekly by injection and is often compared to GLP-1s because the effects (and side effects) overlap, but it tends to have stronger A1c reduction and weight loss effects
On an international scale, there are two officially sanctioned sources 137 Cs and 60 Co
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