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The foundational 2012 paper reporting Dihexa's cognitive-enhancing effects received a formal expression of concern from the journal (PMID: 34551989), citing questions about data integrity including Western blot images
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The peptide has also been reported to interact with central dopaminergic and serotonergic axes: rodent behavioral studies describe effects on neuroplasticity, GABAergic tone, and stress response
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Vitamin B12 deficiency from the perspective of a practicing hematologist
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