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Together, they relax blood vessels and slow the heart rate, making it easier for the heart to pump blood, which ultimately lowers blood pressure
In addition, in vitro studies have shown that recombinant TTR amyloid aggregates are internalized by human cardiac fibroblasts, which subsequently secrete IL-6 and IL-8, providing mechanistic evidence that TTR aggregates can trigger inflammatory responses in cardiac cells [77]
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Apply hydroquinone topically at night (24% concentration) and take oral glutathione (500mg twice daily) to combine fast localised depigmentation with systemic antioxidant support
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