Furthermore, hydroxyalanine has emerged as a prospective marker for diagnosing psoriatic arthritis (103), while variations in levels of circulating metabolites are correlated with the activity and severity of the condition (121, 122)
Mechanistically, kefiran (KE) and kefir exo-polysaccharides (KEPS), as well as KPs, inhibit key inflammatory signaling pathways including NF-B, p-MAPK, p-IkB, pp38, and p-JNK, thereby reducing epithelial cell activation, synovitis, macrophage-mediated inflammation, and cytokine overproduction in systemic and localized inflammatory conditions (Chuang et al., 2023
So attaching an ethyl group to the third carbon of the molecule gives it some cool perks: In a formula, it does the 3 classic vitamin C jobs: it acts as an antioxidant, helps brighten skin tone by inhibiting tyrosinase, and supports collagen
Nakajima H, Amano W, Fujita A, Fukuhara A, Azuma YT, Hata F, Inui T, Takeuchi T
Expect 30 to 40% improvement in wrinkle depth on mild-to-moderate photodamage over 12 to 16 weeks