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Impaired Glutathione Conjugation: The main factor that impairs glutathione conjugation is glutathione depletion
Mitochondrial dysfunction and the resulting oxidative stress in cochlear cells may arise from inherited mitochondrial DNA (mtDNA) mutations, which are associated with aminoglycoside-induced ototoxicity and hereditary hearing loss
"The antioxidant glutathione." Vitam Horm
American Journal of Translational Research, 10 (11), 3322-3329
Model: Female US NIH National Institute on Aging (NIA) Aged Rodent Colony mice aged 22 months Dosage: 10 mg/kg of 5-amino-1MQ administered with subcutaneous injections for eight weeks
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