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In the future, there is a need to combine multi-omics technology to analyze the metabolic heterogeneity, develop multiple inhibitors targeting the compensatory pathway, and improve the killing effect of cancer cells through the combination of glutamine metabolism inhibition with immune checkpoint blockade, CAR-T therapy, and other applications
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Thus FOXO4-DRI may be investigated for those conditions
However, appetite suppression can increase the risk of falling, age-related muscle and bone density loss, hypoglycemia misdiagnosis, and nutrient deficiencies
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