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Diarrhea : Some patients experience loose stools or frequent bowel movements, particularly when starting the medication

It is also important to discuss warning signs that require immediate medical attention, such as severe abdominal pain, persistent vomiting, signs of pancreatitis or gallbladder disease, dehydration, reduced urine output, or worsening anxiety or mood changes

Thus, in perfect agreement with the recent ADA-EASD consensus report [6], we also encourage the adoption of GLP-1RA plus SGLT2i combination therapy in T2DM patients with established ASCVD (coronary artery disease, cerebrovascular disease, or peripheral arterial disease) or multiple risk factors for ASCVD (i.e., age 55 years, obesity, dyslipidemia, hypertension, current tobacco use, left ventricular hypertrophy, and/or proteinuria) whose HbA1c remains suboptimal despite initial treatment with only one of these agents

If they approve your request, youre good to go

Investigations comparing topical GHK-Cu with common dermatologic comparators reported indications of higher dermal procollagen, along with observations consistent with thicker and more elastic skin architecture over multi-week intervals