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A 2024 meta-analysis of 35 RCTs found selenium supplementation significantly reduced TPO antibodies, TSH, and oxidative stress markers in Hashimoto's patients - effects mediated through the GPx-glutathione system
Although it is critical for maintaining good health, it is not considered an essential protein since the human body can make it, as opposed to needing to get it through the diet
Most people then feel either neutral or noticeably better as the deficiency corrects
It is widely used in beauty supplements, injections, and drinks as a component for melanin suppression, liver function support, fatigue recovery, and skin whitening/clarity care