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One should also consider that bacterial fermentation processes can convert the amino acids lysine, ornithine, and tyrosine into cadaverine, putrescine, and tyramine, which can be problematic in biogenic amine intolerance

It appears that that oxidative stress plays a significant role in the toxicity of mycotoxins [31,32,33,34]

& Bungau, S

[26] The mechanical refrigerator (first patented in the 1850s in Europe) liberated brewers and winemakers from seasonal constraints for the first time and allowed them to exit cellars and other earthen environments