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Step 6: Review the Results Check the estimated concentration, mL per dose, syringe measurement, and doses per vial

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In moderate-to-severe hepatic impairment (Child-Pugh B or C), bupropion exposure increases significantly, and the label recommends dose reduction to 150 mg every other day for Child-Pugh B and 75 mg daily for Child-Pugh C [2]

For patients, the cost burden is most acute in therapeutic categories where generic alternatives are not clinically interchangeable due to device differences