Powers MA, Bardsley JK, Cypress M et al (2020) Diabetes self-management education and support in adults with type 2 diabetes: a consensus report of the American Diabetes Association, the Association of Diabetes Care and Education Specialists, the Academy of Nutrition and Dietetics, the American Academy of Family Physicians, the American Academy of PAs, the American Association of Nurse Practitioners, and the American Pharmacists Association
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It suggests that initiating treatment with GLP-1 agonists may be more effective than metformin in reducing dementia risk among individuals with type 2 diabetes
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Furthermore, the dysfunctional ETC produces more ROS due to incomplete oxygen reduction, damaging all kinds of mitochondrial proteins [129]