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doi: 10.1016/j.ejphar.2016.10.016 153 BaiYLianPLiJZhangZQiaoJ
In vitro , MUFA has shown the ability to induce the expression of the adiponectin gene via PPAR activation, which would result in decreased production of pro-inflammatory molecules such as IL-6 and tumour necrosis factor (TNF)-alpha (139) Polyunsaturated fatty acids, such as omega-3 fatty acids (n-3 PUFA), are mostly found in eggs, nuts, and fish, whereas omega-6 fatty acid (n-6 PUFA) is predominantly present in sunflower and other vegetable oils
Its mechanism encompasses insulin resistance (IR), chronic inflammation, oxidative stress, mitochondrial dysfunction, and protein metabolism imbalance(see Figure 1)
This preference shift is a documented effect of GLP-1 activation
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