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The absolute risk increase for diabetic retinopathy complications was greater among patients with a history of diabetic retinopathy at baseline (semaglutide 8.2%, placebo 5.2%) than among patients without a known history of diabetic retinopathy (semaglutide 0.7%, placebo 0.4%)

However, its been found that oral B12 supplementation when taken in high doses can have similar protective effects

Anti-Inflammatory Effects & Mucosal Protection Chronic inflammation underlies many GI conditions, from Crohns disease to IBS

The point is not to self-administer from a guide, but to be an informed participant in a clinical conversation