Many of the cardiovascular and metabolic trials informing the discussion were not designed to evaluate ophthalmic outcomes. The authors called for prospective ophthalmology-specific studies incorporating imaging biomarkers, visual outcomes and disease-specific monitoring, noting that parsing the protective benefits or adverse effects of this rapidly growing medication class will be essential to refining disease management and improve patient outcomes. As GLP-1 therapies become increasingly common among patients with diabetes, obesity and vascular comorbiditiesprecisely the populations populating ophthalmic clinicsthe field may not have the luxury of waiting for cleaner data
These bioactives activate macrophages, dendritic cells, and natural killer (NK) cells, thereby strengthening immune surveillance
doi:10.1111/dom.16343 Lincoff AM, Brown-Frandsen K, Colhoun HM, et al
Excess accumulation of fat in the liver is known as fatty liver disease
Indeed, dulaglutide shows sex-specific treatment differences, as males reduce their intake levels more than females, and the treatment effect persists after discontinuation in males but not in females (Vallof et al., 2020)