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Data from TriNetX are available to researchers on application to TriNetX following the steps outlined here: Source data for Figs
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This Ca 2+ efflux is carried out by either the NCX1 (Na + -Ca 2+ exchanger 1: encoded by the SLC8A1 gene) or the PCMA1b (plasma membrane Ca 2+ transporter 1b: encoded by the ATP2B1 gene) transporters
The results showed that JMF4073 inhibits both TMPK and CMPK at a similar IC 50 , 0.17 M, whereas YMU1 is less potent to CMPK (Fig
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