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Acknowledgements The authors thank the Imperial College Facility for Imaging by Light Microscopy (FILM) for technical support on light microscopy experiments, Dr Jorge Bernardino de la Serna, National Heart and Lung Institute (NHLI), Imperial College London and Dr Affiong I

Poorly controlled diabetes in pregnancy increases the maternal risk for diabetic ketoacidosis, preeclampsia, spontaneous abortions, preterm delivery, and delivery complications