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Am J Physiol Lung Cell Mol Physiol 291 : L46L57 Hu S, Zhao H, Al-Humadi NH, Yin XJ, Ma JK 2006 Silica-induced apoptosis in alveolar macrophages: evidence of in vivo thiol depletion and the activation of mitochondrial pathway

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Moreover, glutamine is an important source of amide nitrogen for nucleotide synthesis, and it contributes to the activation of the mTORC1 pathway which promotes mTORC1-dependant metabolic reprogramming, increasing the proliferation and growth of tumors [36-40]

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