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Macrophage trafficking, inflammatory resolution, and genomics in atherosclerosis: JACC Macrophage in CVD Series (part 2)
Recent scientific studies have demonstrated that oxidative stress accelerates cellular aging by inducing telomere shortening [1]
This selectivity was demonstrated in a study by Raun et al
In this context, several sensors and pathways regulating the transcription factors, such as activator protein 1 (AP-1), cAMP response element-binding protein (CREB), hypoxia inducible factor-1 (HIF-1), nuclear factor B (NF-B), activating transcription factor 4 (ATF-4), and nuclear factor-erythroid 2-related factor-2 (Nrf2), have been described (Marinho et al
W., Vavvas D
