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When inflammation-related cellular dysfunction is considered, the revised RT-qPCR data further highlight alterations in neurotrophic signalling pathways, in line with experimental work showing that GLP1 receptor activation enhances cAMP/PKAdependent CREB signalling and BDNF expression in the diabetic and degenerating brain [30,39]

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Even so, the committee discussed its potential for wound healing and inflammatory conditions like eczema and inflammatory bowel disease