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Storage: Store vials in a climate-controlled environment at or below -20C

Children should start at ~1/4 of adult (2 pumps per day) dosage and work up

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As individuals age, the capacity for glutathione synthesis naturally declines, creating a progressive deficit that may contribute to age-related cellular dysfunction and disease susceptibility

Pregnancy and breastfeeding increase B12 requirements, and pregnant women with B12 deficiency may need more frequent monitoring and potentially adjusted treatment schedules