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Although these findings do not conclusively rule out SARS-CoV-2 infection of the CNS, the evidence suggests that it is unlikely and neurological manifestations of infection may be largely due to systemic inflammatory responses to infection, as well as peripheral organ injury

Nitric oxide treatment attenuates muscle atrophy during hind limb suspension in mice

302,303,304,305 GLP-1R signaling, through PKA, inhibits this process, possibly by promoting IB stability or inhibiting its phosphorylation, thus reducing NF-B activation and nuclear translocation

Therefore, therapies based on antioxidants and/or vasodilators have been postulated as strategies to prevent and/or reduce the progression of NIHL in several animal models and humans

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