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Given that more than half of total knee and hip arthroplasty patients meet criteria for obesity or morbid obesity, weight loss strategies, particularly pharmacologic approaches like GLP-1 receptor agonists, are becoming increasingly relevant in optimizing surgical outcomes and mitigating complications
Who Each Medication Might Suit Patient Profiles Tirzepatide Good Fit If You Want: A well-studied, clinically proven option Steady, predictable fat loss and metabolic support An accessible medication now (current approval and availability) Balanced results with moderate side-effect profile Retatrutide May Be Ideal If You Want: A next-generation therapy with stronger fat-loss potential Deeper metabolic shift and body-composition changes A more aggressive approach and are open to an investigational therapy with close supervision The possibility of enhanced energy expenditure and fat oxidation beyond appetite suppression At Everest, we believe the right choice depends on your goals, health history, metabolic profile, and readiness for advanced care not on hype or trends
