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the placebo group regained roughly two-thirds of what they had lost over the following year

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This distinction matters for quality assurance

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Given that distinct microbial derivatives act through unique molecular targets and pathways to regulate the enteric nervous system (ENS), this review adopts a categorical approach to elucidate the mechanisms underlying their crosstalk more clearly within the gut microbiota-ENS axis ( Figure 3 )

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Secondary outcomes were evaluation of body composition parameters, total adverse events (TAEs) and severe adverse events (SAEs)

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Semaglutide promotes weight loss by mimicking GLP-1 hormones to suppress appetite

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