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About this article Cite this article Hammoud, R., Drucker, D.J

While large clinical trials in type 1 diabetes showed that metformin had little effect on A1C and body weight, other research has shown that the same group does benefit from metformin, particularly for addressing insulin resistance

Remove the needle and dispose of the syringe in your sharps container

Among the forms of ADN, Cardiovascular Autonomic Diabetic Neuropathy (CADN) presents the highest mortality rate (Elafros and Callaghan, 2023), as it impairs both sympathetic and parasympathetic nerves (Feldman et al., 2019)

Keep in mind: specific numbers will shift as Orforglipron launches and contracts are signed, but the economic logic and tradeoffs described here are exactly what youll face when you and your clinician choose a therapy