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Collectively, these insights position GLP-1 and its analogs as versatile and promising agents in the broader context of metabolic disease management

Some important considerations include: Who Should Avoid GLP-1 : Individuals with a history of thyroid cancer, pancreatitis, or severe gastrointestinal issues should avoid GLP-1 agonists

The washout allows tirzepatide levels (half-life 5 days) to drop substantially before adding a new triple agonist

Semaglutide has been associated with modest increases in heart rate (average 24 beats per minute) in clinical trials