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For example, the SELECT trial clearly demonstrated that semaglutide significantly reduces the risk of major adverse cardiovascular events (MACE), leading to FDA approval for lowering the risk of cardiovascular death, myocardial infarction, or stroke in overweight or obese adults with established cardiovascular disease (Lincoff et al., 2023

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Its a synthetic version of a protein naturally found in human digestive fluid

There is, however, a short-term spike in thyroid cancer diagnoses within the first year of initiation, likely due to increased surveillance (i.e., more thyroid ultrasounds and monitoring), not a direct causal effect

The complication of minimal encephalopathy may cause mental disorders in patients with cirrhosis