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Awasthi YC et al

A 2024 trial found a cream with 5% alpha-arbutin and 2% kojic acid worked about as well as a prescription melasma cream but with fewer side effects

Glutathione is a very powerful antioxidant that works against the formation of free radicals, which can cause cellular damage

Functional complementation of anthocyanin sequestration in the vacuole by widely divergent glutathione S-transferases

at Erasmus University Medical Center in the Netherlands, the peptide is based on the FOXO4 domain that binds p53, but synthesized with D-amino acids in reverse order to create a protease-resistant mirror image that retains binding activity